Substantia nigra pars compacta volume

Biomarker

1 paper3 findings

  • Humans1

Associations

3

Age

mixedin humans1

1 study
  1. Substantia nigra pars compacta volume is associated with age in humans.

    “SNc volume correlated significantly with aging in PD.”

    HumansParkinson's diseasesubstantia nigra pars compacta

    Neuromelanin-sensitive MRI correlates of cognitive and motor function in Parkinson's disease with freezing of gait

    Frontiers in dementia11 Aug 2023

Motor symptoms and cognitive measures

mixedin humans1

1 study
  1. Substantia nigra pars compacta volume is associated with motor symptoms and cognitive measures in humans.

    “SNc volume correlated significantly with motor symptoms and cognitive measures in PD with FOG, but not in PD without FOG.”

    HumansParkinson's disease with freezing of gait; correlations were not significant without freezing of gaitsubstantia nigra pars compacta

    Neuromelanin-sensitive MRI correlates of cognitive and motor function in Parkinson's disease with freezing of gait

    Frontiers in dementia11 Aug 2023

Parkinson's disease

downin humans1

1 study
  1. Parkinson's disease is associated with substantia nigra pars compacta volume in humans.

    “SNc volume was significantly decreased in PD with FOG compared to controls.”

    HumansParkinson's disease with freezing of gait compared with healthy older adult controlssubstantia nigra pars compacta

    Neuromelanin-sensitive MRI correlates of cognitive and motor function in Parkinson's disease with freezing of gait

    Frontiers in dementia11 Aug 2023

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