SPP1-high tumor-associated macrophage abundance

1. Smoking is associated with SPP1-high tumor-associated macrophage abundance in humans.

   HumansHPV-negative oral cavity squamous cell carcinomaoral cavity tumorn = 19

   Age-associated transcriptional programs in tumor-associated macrophages are associated with tumor progression in HPV-negative oral cancer

   bioRxiv·8 Oct 2026Preprint

More on Smoking

1. Older age is associated with SPP1-high tumor-associated macrophage abundance in humans.

   HumansHPV-negative oral cavity squamous cell carcinomaoral cavity tumorn = 19

   Age-associated transcriptional programs in tumor-associated macrophages are associated with tumor progression in HPV-negative oral cancer

   bioRxiv·8 Oct 2026Preprint