Splicing programs

Splicing programs improve age prediction in silico (significant improvement in 46 of 76 tissue-cell types).

“In mice, integrating SPs with gene expression significantly improved age prediction in 46 of 76 tissue-cell types tested.”

In silicointegrating splicing programs with gene expression46 of 76 tissue-cell types tested

Aging-associated alternative splicing programs conserved between human and mouse tissues

bioRxiv (Cold Spring Harbor Laboratory)·31 Dec 2025Preprint