Spike-specific CD4+ T cells

3 papers study it3 more mention it1 finding

Human trial1
Humans2

Associations

1

Anti-S1 IgG

upin humans1

1 study

Spike-specific CD4+ T cells are associated with anti-S1 IgG in humans.
“pre-existing spike-specific CD4+ T cells are associated with efficient induction of anti-S1 IgG and neutralizing capacity in serum but not saliva”
Human trial
Cutting Edge: Serum but Not Mucosal Antibody Responses Are Associated with Pre-Existing SARS-CoV-2 Spike Cross-Reactive CD4⁺ T Cells following BNT162b2 Vaccination in the Elderly
Journal of immunology (Baltimore, Md. : 1950)Feb 4, 2022

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