Skeletal muscle epigenetic clock

Skeletal muscle epigenetic clock predicts chronological age in silico (MAE 5.537 years).

“Machine learning models built on these CpG sites showed high prediction accuracy, with mean absolute errors of 5.537 years in sequencing”

In silicoNext-Generation Sequencing (NGS) platformpectoralis major musclen = 103

Epigenetic aging signatures and age prediction in human skeletal muscle

Aging·26 Nov 2025