Serum Klotho

1. Caffeine is associated with serum Klotho in humans (-3.40 pg/mL per additional 100 mg caffeine; 95% CI -5.73 to -1.07).

   “with each additional 100 mg of dietary caffeine consumption, Klotho decreased by 3.40 pg./mL (95% confidence interval [CI]: -5.73, -1.07).”

   HumansAdjusted for covariatesserumEach additional 100 mg of dietary caffeine consumptionn = 11,169

   Dietary caffeine and its negative link to serum Klotho concentrations: evidence from the National Health and Nutrition Examination Survey

   Frontiers in nutrition·11 Dec 2024

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