Seroconversion rate

1. Cvd 1926 dleted increases seroconversion rate in mice (83% vs 42%).

   “After two immunizations, the proportion of seroconverters for CVD 1926 ΔsteD was 83% (10/12) compared to 42% (5/12) for CVD 1926.”

   Animalsn = 12

   Deletion of an immune evasion gene, steD, from a live Salmonella enterica serovar Typhimurium vaccine improves vaccine responses in aged mice

   Frontiers in immunology·Jun 7, 2024

More on Cvd 1926 dleted

1. IIV4 + PPV23 is associated with seroconversion rate in humans.

   “Furthermore, co-administration of IIV4 and PPV23 affected seroconversion rates for both vaccines.”

   Human trialhealthy adults

   Immunogenicity and safety of different combinations involving a third booster dose of SARS-CoV-2 inactivated vaccine, inactivated quadrivalent influenza vaccine, and 23-valent pneumococcal polysaccharide vaccine in adults aged ≥60 years: a phase 4, randomized, open-label study

   Frontiers in immunology·Aug 20, 2024

More on IIV4 + PPV23