Senescent RBC count

Biomarker

1 paper1 finding

  • Animals1

Interventions

1

Clodronate liposomes

upin mice1

1 study
  1. Clodronate liposomes increase senescent RBC count in mice.

    “Depletion of macrophages by administration of clodronate-loaded liposomes resulted in a significant decrease in the mean expression of CD47 on RBCs of all age groups and a significant accumulation of senescent RBCs in blood and spleen.”

    Animalsmacrophage depletion

    Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation

    Transfusion1 Sep 2007

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