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Retroelement epigenetic clock

Biomarker

2 papers study it7 findings

See all 2

  • Humans1
  • In silico1

Interventions

3

Antiretroviral therapy

downin humans2

2 studies

  1. Antiretroviral therapy decreases retroelement epigenetic clock in humans.

    “responsive to antiretroviral therapy”

    Humansin people living with HIV-1

    Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements

    Aging cell

  2. Antiretroviral therapy decreases retroelement epigenetic clock in humans.

    “responsive to antiretroviral therapy”

    Humansin people living with HIV-1

    Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states

    bioRxiv : the preprint server for biologyPreprint

More on Antiretroviral therapy

Transient epigenetic reprogramming

downin cells1

1 study

  1. Transient epigenetic reprogramming decreases retroelement epigenetic clock in cells.

    “retroelement-based epigenetic clocks were reversed during transient epigenetic reprogramming”

    Cells

    Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements

    Aging cell

More on Transient epigenetic reprogramming

Transient reprogramming

downin silico1

1 study

  1. Transient reprogramming decreases retroelement epigenetic clock in silico.

    “retroelement epigenetic clocks were reversed during transient epigenetic reprogramming”

    In silicotransient epigenetic reprogramming

    Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states

    bioRxiv : the preprint server for biologyPreprint

More on Transient reprogramming

Upstream

1

HIV-1 infection

upin humans1

1 study

  1. HIV-1 infection increases retroelement epigenetic clock in humans.

    “accelerated in people living with HIV-1”

    Humansin people living with HIV-1

    Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements

    Aging cell

More on HIV-1 infection

Associations

2

Chronological age

upin silico1

1 study

  1. Retroelement epigenetic clock predicts chronological age in silico.

    “locus-specific retroelement DNA methylation can be used to create retroelement-based epigenetic clocks that accurately measure chronological age in the immune system, across human tissues, and pan-mammalian species.”

    In silico

    Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements

    Aging cell

HIV-1 infection

upin humans1

1 study

  1. HIV-1 infection is associated with retroelement epigenetic clock in humans.

    “accelerated in people living with HIV-1”

    HumansHIV-1 infection

    Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states

    bioRxiv : the preprint server for biologyPreprint

More on HIV-1 infection

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