Presence of clinically relevant markers

Male sex is associated with presence of clinically relevant markers in humans (At least one clinical marker: 15% versus 13% with MDRD eGFR 45–59; 41% versus 21% with eGFR <45 mL/min/1.73 m(2)).

“Moderately decreased eGFR is more often associated with clinical markers in men than in women.”

Humansmoderately decreased eGFR4 yearsmen versus womensn = 1,298

Epidemiology and prognostic significance of chronic kidney disease in the elderly--the Three-City prospective cohort study

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·15 Jun 2011