Polyploid cells

1 paper2 findings

Model organisms1

Interventions

2

Dietary restriction

downin flies1

1 study

Dietary restriction decreases polyploid cells in flies.
“Flies aged at a low temperature, or with a low protein diet, accumulate polyploid cells in the brain more slowly than expected”
Model organismswith a low protein dietbrain
Cell cycle re-entry in the aging Drosophila brain
bioRxiv : the preprint server for biologyAug 26, 2024Preprint

More on Dietary restriction

Cold

downin flies1

1 study

Cold decreases polyploid cells in flies.
“Flies aged at a low temperature, or with a low protein diet, accumulate polyploid cells in the brain more slowly than expected”
Model organismsaged at a low temperaturebrain
Cell cycle re-entry in the aging Drosophila brain
bioRxiv : the preprint server for biologyAug 26, 2024Preprint

Latest

1 in 12 months

Advances in Experimental Medicine and BiologyMay 22

Polyploidy and Senescence of Cancer Cells: Impact of Cell Fusion

ReviewCellular senescence

bioRxivNov 24

Changes in cell size occur across brain regions in the aging Drosophila brain

Preprint: experiments in fliesMechanisms

GeneticsAug 1

Activation of a Src-JNK pathway in unscheduled endocycling cells of the Drosophila wing disc induces a chronic wounding response

Experiments in fliesJNK signalling

bioRxivMar 31

Activation of a Src-JNK pathway in unscheduled endocycling cells of the Drosophila wing disc induces a chronic wounding response

Preprint: experiments in fliesJNK signalling

Cell Death DiscoveryOct 14

Polyploidy mitigates the impact of DNA damage while simultaneously bearing its burden

Experiments in miceDNA damage response

bioRxivSep 10

Cell cycle re-entry in the aging Drosophila brain

Preprint: experiments in fliesInterventions

bioRxivOct 23

The consequences of tetraploidy on Caenorhabditis elegans physiology and sensitivity to chemotherapeutics

Preprint: experiments in wormsMechanisms

Journal of Cell ScienceOct 16

Epithelial mechanics are maintained by inhibiting cell fusion with age in Drosophila

Experiments in fliesMechanisms

International Journal of Molecular SciencesApr 13

Polyploidy as a Fundamental Phenomenon in Evolution, Development, Adaptation and Diseases

ReviewMechanisms

bioRxivAug 9

Blocking cell fusion inhibits age-induced polyploidy and maintains epithelial organization in Drosophila

Preprint: experiments in model organismsMechanisms