Poly-ADP-ribose

2 papers study it13 more mention it

Animals1
Cells1

Latest

2 papers in 12 months

Aging CellDec 24

Promising Results With NAD Supplementation in Rare Diseases With Premature Aging and DNA Damage

ReviewInterventions

bioRxivDec 4

PARP1 deficiency induces aging-associated cardiac failure via activation of Akt signalling

Preprint: experiments in miceMechanisms

Molecular Cancer TherapeuticsOct 12

Targeting NAD+ Metabolism Vulnerability in FH-Deficient Hereditary Leiomyomatosis and Renal Cell Carcinoma with the Novel NAMPT Inhibitor OT-82

Experiments in miceRenal cell carcinoma

Cell Death & DiseaseOct 2

Inhibition of poly(ADP-Ribosyl)ation reduced vascular smooth muscle cells loss and improves aortic disease in a mouse model of human accelerated aging syndrome

Experiments in miceInterventions

Biochemical and Biophysical Research CommunicationsJul 6

NAD⁺ overconsumption by poly (ADP-ribose) polymerase (PARP) under oxidative stress induces cytoskeletal disruption in vascular endothelial cell

Experiments in human cellsInterventions

Ageing Research ReviewsJan 27

PARP1 at the crossroad of cellular senescence and nucleolar processes

ReviewCellular senescence

Toxicology and Applied PharmacologyDec 29

NMNATs expression inhibition mediated NAD⁺ deficiency plays a critical role in doxorubicin-induced hepatotoxicity in mice

Experiments in miceInterventions

The Journal of Reproduction and DevelopmentJan 1

NAD⁺, Sirtuins and PARPs: enhancing oocyte developmental competence

ReviewInterventions

DNA RepairJun 8

DNA damage and regulation of protein homeostasis

ReviewMechanisms

Current Medicinal ChemistryJan 19

NAD Precursors, Mitochondria Targeting Compounds and ADP-Ribosylation Inhibitors in Treatment of Inflammatory Diseases and Cancer

ReviewInterventions