Plaque macrophage content
Biomarker1 paper1 finding
- Animals1
Interventions
1Rapamycin
downin mice1Very low certainty
1 study
Rapamycin
downin mice1Very low certainty
Rapamycin decreases plaque macrophage content in mice (0.73 ± 0.07 vs 0.95 ± 0.09 × 105 μm2, p < 0.05).
Animalsestablished atherosclerotic lesionsintraperitonealatherosclerotic plaquetriweekly8 weeksmales
Therapeutic Immune Reprogramming by Rapamycin Attenuates Plaque Inflammation and Lymphoid Immune Responses in Aged Atherosclerotic Mice · Aging cell · 23 Sep 2026