Pituitary GHRH receptor-binding affinity

1. Sermorelin improves pituitary GHRH receptor-binding affinity in rats.

   “treatment with 1.0 mg/kg GHRH restored the affinities of high and low affinity classes of GHRH-binding sites”

   Animalsrestoration toward values in 2-month-old ratshuman GHRH-(1-29)NH2pituitary1.0 mg/kg BW daily14 daysmales

   Differential in vivo regulation of the pituitary growth hormone-releasing hormone (GHRH) receptor by GHRH in young and aged rats

   Endocrinology·Jun 1, 1999

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