High-affinity pituitary GHRH receptor-binding sites

1 paper studies it2 findings

Interventions

Sermorelin

downin rats1upin rats1

1 study

Sermorelin decreases high-affinity pituitary GHRH receptor-binding sites in rats (2.4-fold decrease versus 0.5 mg/kg BW; P < 0.05).
“Treatment with 1.0 mg/kg GHRH decreased the number of high affinity pituitary GHRH-R-binding sites by 2.4-fold compared with that in rats treated with 0.5 mg/kg BW”
Animalscompared with 0.5 mg/kg BWhuman GHRH-(1-29)NH2pituitary1.0 mg/kg BW daily14 daysmales
Differential in vivo regulation of the pituitary growth hormone-releasing hormone (GHRH) receptor by GHRH in young and aged rats
EndocrinologyJun 1, 1999
Sermorelin increases high-affinity pituitary GHRH receptor-binding sites in rats (2-fold).
“treatment with 0.5 mg/kg GHRH increased the number of high affinity pituitary GHRH-R-binding sites by 2-fold (P < 0.05)”
Animalshuman GHRH-(1-29)NH2pituitary0.5 mg/kg BW daily14 daysmales
Differential in vivo regulation of the pituitary growth hormone-releasing hormone (GHRH) receptor by GHRH in young and aged rats
EndocrinologyJun 1, 1999

EndocrinologyJun 1

Experiments in ratsInterventions