Phenotypic Aging Index

Biomarker

1 paper5 findings

  • Humans1

Associations

5

Long-term hospitalization

upin humans1OR 1.29

1 study
  1. Phenotypic Aging Index predicts long-term hospitalization in humans (OR 1.29, 95% CI 1.00-1.66).

    “long-term hospitalization (OR, 1.29; 95% CI, 1.00-1.66)”

    Humansn = 13,879

    Physiological Phenotypic Aging Index and Its Association With Health, Functional, and Health Care Outcomes in Older Adults: Findings From the UK Biobank

    Journal of the American Medical Directors Association18 Oct 2025

Physical function

downin humans1OR 4.48

1 study
  1. Phenotypic Aging Index predicts physical function in humans (OR 4.48, 95% CI 3.21-6.22).

    “physical function decline (OR, 4.48; 95% CI, 3.21-6.22)”

    Humansn = 13,879

    Physiological Phenotypic Aging Index and Its Association With Health, Functional, and Health Care Outcomes in Older Adults: Findings From the UK Biobank

    Journal of the American Medical Directors Association18 Oct 2025

Disability

upin humans1OR 1.36

1 study
  1. Phenotypic Aging Index predicts disability in humans (OR 1.36, 95% CI 1.190-1.57).

    “disability (OR, 1.36; 95% CI, 1.190-1.57)”

    Humansn = 13,879

    Physiological Phenotypic Aging Index and Its Association With Health, Functional, and Health Care Outcomes in Older Adults: Findings From the UK Biobank

    Journal of the American Medical Directors Association18 Oct 2025

Multimorbidity

upin humans1OR 1.69

1 study
  1. Phenotypic Aging Index predicts multimorbidity in humans (OR 1.69, 95% CI 1.48-1.93).

    “multimorbidity [odds ratio (OR), 1.69; 95% CI, 1.48-1.93]”

    Humansn = 13,879

    Physiological Phenotypic Aging Index and Its Association With Health, Functional, and Health Care Outcomes in Older Adults: Findings From the UK Biobank

    Journal of the American Medical Directors Association18 Oct 2025

More on Multimorbidity

Mortality

upin humans1HR 1.84

1 study
  1. Phenotypic Aging Index predicts mortality in humans (HR 1.84, 95% CI 1.26-2.70).

    “The PAI significantly predicted mortality (hazard ratio, 1.84; 95% CI, 1.26-2.70)”

    Humansn = 13,879

    Physiological Phenotypic Aging Index and Its Association With Health, Functional, and Health Care Outcomes in Older Adults: Findings From the UK Biobank

    Journal of the American Medical Directors Association18 Oct 2025

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