PhenoAge EAA

Biomarker

2 papers2 findings

  • Humans1

Associations

2

Frailty

upin humans1

1 study
  1. PhenoAge EAA is associated with frailty in humans (standardised β 0.07 (95% CI 0.03-0.11)).

    “PhenoAge EAA (eight studies; n=10 371; 0·07 [0·03-0·11], I2=81·7%), GrimAge EAA (eight studies; n=10 371; 0·11 [0·06-0·15], I2=90·5%)”

    Reviewn = 10,371

    Biological age measured by DNA methylation clocks and frailty: a systematic review and meta-analysis

    The lancet. Healthy longevity6 Nov 2025

Adverse childhood experiences

upin humans1

1 study
  1. Adverse childhood experiences are associated with PhenoAge EAA in humans.

    “Among Hispanic women, Socioeconomic Adversity was linked to higher PhenoAge EAA and faster DunedinPoAm pace relative to those in the Parental Low Education group.”

    Humansamong Hispanic womenfemales

    Adverse childhood experiences patterns and biological aging in a representative sample of older Americans

    Psychoneuroendocrinology5 Nov 2025

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