PhenoAge and GrimAge acceleration

1 paper3 findings

Humans1

Interventions

1

Physical activity

no changein humans1

1 study

Physical activity has no effect on PhenoAge and GrimAge acceleration in humans.
“However, self-reported PA was not associated with the epigenetic age accelerations.”
HumansJapanese participants; self-reported physical activityperipheral bloodn = 867
Influence of physical activity on the epigenetic clock: evidence from a Japanese cross-sectional study
Clinical epigeneticsOct 15, 2024

More on Physical activity

Associations

2

Sedentary time

upin humans1

1 study

Sedentary time is associated with PhenoAge and GrimAge acceleration in humans.
“Multivariable regression analysis showed that accelerometer-based PA and sedentary time were associated with epigenetic age decelerations and accelerations, respectively.”
HumansJapanese participants; accelerometer-based sedentary timeperipheral bloodn = 867
Influence of physical activity on the epigenetic clock: evidence from a Japanese cross-sectional study
Clinical epigeneticsOct 15, 2024

More on Sedentary time

Physical activity

downin humans1

1 study

Physical activity is associated with PhenoAge and GrimAge acceleration in humans.
“Multivariable regression analysis showed that accelerometer-based PA and sedentary time were associated with epigenetic age decelerations and accelerations, respectively.”
HumansJapanese participants; accelerometer-based physical activityperipheral bloodn = 867
Influence of physical activity on the epigenetic clock: evidence from a Japanese cross-sectional study
Clinical epigeneticsOct 15, 2024

More on Physical activity

Latest

1 in 12 months

medRxivSep 9

WHO-Recommended Exercise Dose Is Associated With Slower Epigenetic Aging in Older Adults

Preprint: non-randomized trial in 72 peopleExercise

bioRxivNov 19

Early-life nutrition supplementation and epigenetic age in middle-adulthood among Guatemalan adults

Preprint: randomized trial in 1,095 peopleInterventions

AgingSep 11

Longitudinal associations of epigenetic aging with cognitive aging in Hispanic/Latino adults from the Hispanic Community Health Study/Study of Latinos

Cohort study of 2,671 peopleBiomarkers

Human GenomicsMay 24

Causal impact of genetically-determined fish and fish oil intake on epigenetic age acceleration and related serum markers

Mendelian randomization in 461,384 peoplePopulations

Journal of Periodontal & Implant ScienceMay 12

Dissecting the causal association of periodontitis with biological aging and its underlying mechanisms: findings from Mendelian randomization and integrative genetic analysis

Mendelian randomization in peopleMechanisms

BiogerontologyJan 8

The protein cargo of extracellular vesicles correlates with the epigenetic aging clock of exercise sensitive DNAmFitAge

Cross-sectional study in peopleBiomarkers

MenopauseDec 3

The prospective association of cellular markers of biological aging with menopause in the Coronary Artery Risk Development in Young Adults Study

Cohort study of 583 peopleBiomarkers

Clinical EpigeneticsOct 16

Influence of physical activity on the epigenetic clock: evidence from a Japanese cross-sectional study

Cross-sectional study of 867 peoplePopulations

BMC Medical GenomicsMay 28

Epigenetic age acceleration is associated with blood lipid levels in a multi-ancestry sample of older U.S. adults

Cross-sectional study of 3,813 peopleGrimAge

International Journal of Aging & Human DevelopmentFeb 13

Sleep Duration Polygenic Risk and Phenotype: Associations with Biomarkers of Accelerated Aging in the Baltimore Longitudinal Study of Aging

Cohort study of 567 peoplePopulations