Periventricular white matter hyperintensities

Biomarker

3 papers2 findings

  • Humans3

Effects

1

Memory functioning

mediatesin humans1

1 study
  1. Periventricular white matter hyperintensities mediate memory functioning in humans (β = -4.1, 95% CI -8.7 to -0.2, p < 0.05).

    “Periventricular WMH volume mediated the effect of dipping status and hypertension on memory (β = -4.1, 95% confidence interval -8.7 to -0.2, p < 0.05).”

    Humanseffect of dipping status and hypertension on memory

    White matter hyperintensities mediate the association of nocturnal blood pressure with cognition

    Neurology15 Apr 2020

Associations

1

Reverse dipping

upin humans1

1 study
  1. Reverse dipping is associated with periventricular white matter hyperintensities in humans (F 2,423 = 3.78, p = 0.024).

    “Reverse dipping in the presence of hypertension was associated with particularly elevated periventricular WMH volume (F 2,423 = 3.78, p = 0.024)”

    Humansin the presence of hypertension

    White matter hyperintensities mediate the association of nocturnal blood pressure with cognition

    Neurology15 Apr 2020

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