Peripheral naïve CD4 and CD8 T-cell numbers
1 paper1 finding
- Animals1
Upstream
1MYC
upin mice1
1 study
MYC
upin mice1
MYC increases peripheral naïve CD4 and CD8 T-cell numbers in mice.
“Constitutive Myc expression in thymic epithelial cells (TEC) of middle-aged mice enhanced thymic function, and increased numbers of peripheral naïve CD4 and CD8 T-cells.”
Animalsconstitutive Myc expression in thymic epithelial cells
Enhancing thymic function improves T-cell reconstitution and immune responses in aged mice
PLoS biology28 Jul 2025
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PLOS Biology
Enhancing thymic function improves T-cell reconstitution and immune responses in aged mice
Experiments in miceBlood and immune system