Parkinson's disease polygenic risk score

1. Parkinson's disease polygenic risk score is associated with REM sleep duration in humans (pcorrected = 0.03 for REM duration, pcorrected = 0.004 for theta energy).

   “In the younger subsample, REM duration and theta energy were positively associated with PD PRS.”

   Humansin younger individuals

   Age-Related Differences in the Association between REM Sleep and the Polygenic Risk for Parkinson's Disease

   Annals of neurology·25 Dec 2025

More on REM sleep duration