There is 1 paper on P53 protein abundance in aging research: none in people yet, 1 in cells.
1 paper studies it1 more mentions it1 finding
See all 2 papers on P53 protein abundance
- Cells1
Upstream
1MDM2
downin rat cells1
1 study
MDM2
downin rat cells1
MDM2 decreases P53 protein abundance in rat cells (decreased Mdm2 expression, reversed by Mdm2 overexpression).
“decreased Mdm2 expression led to senescence-associated phenotypes along with increased p53 and p21 protein abundance, which could all be reversed by Mdm2 overexpression”
Cellsdecreased Mdm2 expression, reversed by Mdm2 overexpression
Biochemical and biophysical research communications
Latest
Biochemical and Biophysical Research Communications
Tempo-spatial alternative polyadenylation analysis reveals that 3' UTR lengthening of Mdm2 regulates p53 expression and cellular senescence in aged rat testis
Experiments in cellsCellular senescence
International Journal of Cardiology
Muscle-specific programmed cell death 5 deletion attenuates cardiac aging
Experiments in miceApoptosis