Papers on p16+ senescent cells

16 papers

Saturday, August 1

EngineeringAug 1

Probio-M9 and Genetic Senolysis Attenuate Experimental Colitis by Targeting Inflammation-Associated Cellular Senescence

Experiments in miceInterventions

Paper

Tuesday, May 5

Journal of Cerebral Blood Flow and MetabolismMay 5

Targeting senescence mitigates the deleterious effects of midlife obesity on neurovascular function by partially restoring blood-brain barrier integrity and neurovascular coupling

Experiments in animalsObesity

Paper

Monday, April 27

bioRxivApr 27

Senescence and DNA Damage-Induced Inflammation Drive Heart Failure with Preserved Ejection Fraction in Cardiovascular Kidney Metabolic Syndrome

Preprint: experiments in miceHeart failure with preserved ejection fraction

Paper

Monday, April 13

American Journal of Physiology Heart and Circulatory PhysiologyApr 13

Plasma metabolites, blood-borne microvesicles, and history of preeclampsia as predictors of coronary artery calcification in postmenopausal women

Case-control study in peopleCoronary artery calcification

Paper

Friday, October 24

Cancer DiscoveryOct 24

p21-Positive Senescent Stromal Cells Promote Prostate Cancer Immune Suppression and Progression That Can Be Reversed by Senolytic Therapy

Study in peopleProstate cancer

Paper

Thursday, May 29

Aging CellMay 29

Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches

Experiments in miceSenolytics

Paper

Sunday, April 7

Molecular TherapyApr 7

A p21-ATD mouse model for monitoring and eliminating senescent cells and its application in liver regeneration post injury

Experiments in miceCellular senescence

Paper

Monday, February 19

Journal of Translational MedicineFeb 19

Senescent fibroblast facilitates re-epithelization and collagen deposition in radiation-induced skin injury through IL-33-mediated macrophage polarization

Experiments in animalsCellular senescence

Paper

Wednesday, May 31

International Journal of Oral ScienceMay 31

RANKL⁺ senescent cells under mechanical stress: a therapeutic target for orthodontic root resorption using senolytics

Experiments in ratsSenolytics

Paper

Friday, May 5

Journal of Assisted Reproduction and GeneticsMay 5

Association between endometrial senescent cells and immune cells in women with repeated implantation failure

Case-control study of 116 peopleCellular senescence

Paper

Thursday, April 20

Aging CellApr 20

Clearance of senescent cells reverts the cigarette smoke-induced lung senescence and airspace enlargement in p16-3MR mice

Experiments in miceCellular senescence

Paper

Thursday, July 14

Frontiers in AgingJul 14

Removal of p16 INK4 Expressing Cells in Late Life has Moderate Beneficial Effects on Skeletal Muscle Function in Male Mice

Experiments in miceMuscle

Paper

Saturday, May 7

JID InnovationsMay 7

IL-34 Downregulation‒Associated M1/M2 Macrophage Imbalance Is Related to Inflammaging in Sun-Exposed Human Skin

Cross-sectional study in peopleInflammation

Paper

Sunday, April 24

Ageing Research ReviewsApr 24

Assessment of cell cycle regulators in human peripheral blood cells as markers of cellular senescence

ReviewBiomarkers

Paper

Tuesday, November 12

Immunity & AgeingNov 12

Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype

Experiments in human cellsCellular senescence

Paper

Tuesday, July 10

Arthritis & RheumatologyJul 10

Salivary Gland Stem Cells Age Prematurely in Primary Sjögren's Syndrome

Experiments in cellsMechanisms

Paper