P-PLN-Thr17

1. Ovariectomy decreases P-PLN-Thr17 in mice (0.38±0.003 vs. 2.2±0.3 (SHAM)).

   “phospho-phospholamban at Thr17 (P-PLN-Thr17) expression was reduced (SHAM 2.2±0.3 vs. OVX-CMI 0.38±0.003)”

   Animalsin female mice with cardiometabolic injury (high-fat diet + L-NAME)heart18 weeksfemales

   Estrogen Deficiency Exacerbates Cardiac Dysfunction in a Female Mouse Model of Cardiometabolic Injury Via Phospholamban Modulation

   AHA Scientific Sessions 2025 abstract·Nov 3, 2025

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