Oocyte proteomic age signature

There is 1 paper on oocyte proteomic age signature in aging research: none in people yet, 1 in animals. The newest story, Nov 2, 2026: “Fertilization can offset age-related egg changes in mice”.

Biomarker

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  • Animals1

Associations

1

In vitro fertilization

mixedin mice1

1 study
  1. In vitro fertilization is associated with oocyte proteomic age signature in mice (comparison with parthenogenetically activated oocytes).

    “Comparison with parthenogenetically activated oocytes showed this divergence to be fertilization-dependent”

    Animalscomparison with parthenogenetically activated oocytesoocyte and blastocyst

    Fertilization can offset age-related egg changes in mice

    bioRxivPreprint

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bioRxiv

Fertilization can offset age-related egg changes in mice

Eggs from aged mice fertilized in the lab formed early embryos at rates comparable to young controls and developed without detectable impairment in young recipients.Eggs from aged mice fertilized in the lab formed early embryos at rates comparable to young controls and developed without detectable impairment in young recipients.

Preprint: mouse studyReproductive system