Nuclear orientation

1. Shear stress increases nuclear orientation in cells (9 degrees on average).

   “nuclear orientation in endothelial cells shifted toward the flow direction by 9 degrees on average for cells at higher passage.”

   Cellshigher passage cells

   Endothelial Nuclear and Cytoskeletal Responses to Mechanical Stresses

   Advances in experimental medicine and biology·1 Jan 2026

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