bioRxiv
Imipramine linked to lower death risk in Alzheimer’s patients
An observational analysis linked imipramine prescriptions to lower mortality over 10 years in Alzheimer’s patients compared with other antidepressants or none.An observational analysis linked imipramine prescriptions to lower mortality over 10 years in Alzheimer’s patients compared with other antidepressants or none.
Preprint: cohort studyAlzheimer's disease
Who was studiedPeople with Alzheimer’s disease, against other antidepressant users or nonusers
What changedPeople prescribed imipramine had fewer deaths from any cause over 10 years than those prescribed other antidepressants or none
The catchHealth or care differences between prescription groups could explain the mortality association