Neurite density index

1. GFAP is associated with neurite density index in humans.

   Humansdementia-freebrainn = 457

   Plasma inflammatory markers and brain white matter microstructure in late middle-aged and older adults · Neurobiology of aging · 21 Sep 2026

GFAP →

1. Neurite density index is associated with VO2max in humans.

   “Across all participants, pre-to-post changes in mean NDI were positively correlated with changes in VO2max, but this association did not differ between groups.”

   Human trialpre-to-post changes across all participantswhite matter8 weeksn = 66

   Physical exercise increases the NODDI-derived neurite density index across white matter tracts in healthy older adults: results from the FIT4BRAIN randomized controlled trial · medRxiv · 4 Sep 2026 · Preprint

VO2max →

1. Chronological age is associated with neurite density index in humans.

   Humanscortico-striato-pallido-thalamic loop white matter tractsn = 104

   Cortico-striato-pallido-thalamic loop: Effects of age on white matter neurite microstructural properties and its spatial gradients · bioRxiv · 24 Aug 2026 · Preprint