What does the research say about N4-acetylcytidine?

N4-acetylcytidine

There are 4 papers on N4-acetylcytidine in aging research: 3 observational studies in people, 1 in animals. The newest story, Nov 2, 2026: “Fungal enzyme structure offers clues to RNA modification”.

Biomarker

4 papers study it8 more mention it

See all 12 papers on N4-acetylcytidine

Humans3
Animals1

Latest

6 papers in 12 months

Clinical and Molecular HepatologyJun 19

NAT10 deficiency in aging drives impaired liver regeneration by disrupting PARP10 in an ac4C-dependent manner

Experiments in miceMechanisms

Paper

Nature CommunicationsSep 17

Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals

Cohort study of 13,512 peopleBiomarkers

Paper

International Journal of EpidemiologyOct 28

Metabolomic profiles associated with all-cause mortality in the Women's Health Initiative

Cohort study of 1,355 peopleBiomarkers

Paper

Nature MedicineJan 17

Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states

Cohort study in peopleMechanisms

Paper

Naunyn-Schmiedeberg's Archives of PharmacologyAug 29

Propofol regulates SLC6A2 expression via NAT10-mediated ac4C modification to modulate excessive mitophagy and hippocampal neuron dysfunction in aged postoperative cognitive dysfunction

Experiments in miceMitophagy

Paper

Biochemical and Biophysical Research CommunicationsJul 2

NAT10-mediated RNA N4-acetylation promotes intestinal fibroblast senescence via DHRS2

Experiments in human cellsCellular senescence

Paper

Nature CommunicationsJun 20

Fungal enzyme structure offers clues to RNA modification

Experiments with purified fungal protein revealed a heart-shaped pair and suggested that RNA positioning, rather than binding strength, drives its chemical modification.Experiments with purified fungal protein revealed a heart-shaped pair and suggested that RNA positioning, rather than binding strength, drives its chemical modification.

Experiments in cellsMechanisms