Modified 5-factor Frailty Index

There are 6 papers on modified 5-factor Frailty Index in aging research: 6 observational studies in people.

Biomarker

6 papers study it12 more mention it6 findings

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“mFI-5 (C-statistic 0.677 [95% CI 0.675-0.679], p < 0.0001, DeLong test)”
Comparison of the Risk Analysis Index and the modified 5-factor frailty index in predicting 30-day morbidity and mortality after spine surgeryJournal of neurosurgery. Spine2023doi:10.3171/2023.2.spine221019
  • Humans6

Associations

5

Mortality

upin humans2

2 studies
  1. Modified 5-factor Frailty Index predicts mortality in humans (emergent and elective inguinal or femoral hernia repairs) (AUC 0.86 emergent, 0.80 elective).

    “Area under the curve was calculated for emergent and elective groups, including mortality (0.86, 0.80)”

    Humansemergent and elective inguinal or femoral hernia repairsn = 41,897

    Assessing the mFI-5 frailty score and functional status in geriatric patients undergoing inguinal hernia repairs

    Hernia : the journal of hernias and abdominal wall surgery

  2. Modified 5-factor Frailty Index predicts mortality in humans (C-statistic 0.677 [95% CI 0.675-0.679], p < 0.0001).

    “mFI-5 (C-statistic 0.677 [95% CI 0.675-0.679], p < 0.0001, DeLong test)”

    Humansn = 292,225

    Comparison of the Risk Analysis Index and the modified 5-factor frailty index in predicting 30-day morbidity and mortality after spine surgery

    Journal of neurosurgery. Spine

Modified 11-factor Frailty Index

upin humans1

1 study
  1. Modified 5-factor Frailty Index is associated with modified 11-factor Frailty Index in humans (ovarian cancer undergoing cytoreductive surgery with HIPEC) (spearman rho 0.98, p < 0.001).

    “mFI5 and mFI11 scores for frailty were highly correlated (spearman rho 0.98, p < 0.001).”

    Humansovarian cancer undergoing cytoreductive surgery with HIPECfemalesn = 141

    The modified 5-factor frailty index predicts postoperative outcomes in patients with ovarian cancer undergoing hyperthermic intraperitoneal chemotherapy

    Surgical oncology

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Discharge to facility or home services

upin humans1

1 study
  1. Modified 5-factor Frailty Index predicts discharge to facility or home services in humans (ovarian cancer undergoing cytoreductive surgery with HIPEC) (22.7 % vs. 6.8 %, 18.2 % vs 8.5 %, p = 0.025).

    “Frail patients were more likely to be discharged to a skilled nursing facility (22.7 %) vs. 6.8 % of non-frail patients, or require home services (18.2 % vs 8.5 %, p = 0.025).”

    Humansovarian cancer undergoing cytoreductive surgery with HIPECfemalesn = 141

    The modified 5-factor frailty index predicts postoperative outcomes in patients with ovarian cancer undergoing hyperthermic intraperitoneal chemotherapy

    Surgical oncology

Postoperative complications

upin humans1OR 3.08

1 study
  1. Modified 5-factor Frailty Index predicts postoperative complications in humans (ovarian cancer undergoing cytoreductive surgery with HIPEC) (OR 3.08, p = 0.024).

    “On multivariable logistic regression, frail patients were more likely to experience moderate or higher Accordion postoperative complications (OR 3.08, p = 0.024).”

    Humansovarian cancer undergoing cytoreductive surgery with HIPECfemalesn = 141

    The modified 5-factor frailty index predicts postoperative outcomes in patients with ovarian cancer undergoing hyperthermic intraperitoneal chemotherapy

    Surgical oncology

Pneumonia

upin humans1

1 study
  1. Modified 5-factor Frailty Index predicts pneumonia in humans (emergent and elective inguinal or femoral hernia repairs) (AUC 0.82 emergent, 0.77 elective).

    “pneumonia (0.82, 0.77), discharge destination not home (0.78, 0.73), prolonged LOS (0.69, 0.66), and infection (0.71, 0.62).”

    Humansemergent and elective inguinal or femoral hernia repairsn = 41,897

    Assessing the mFI-5 frailty score and functional status in geriatric patients undergoing inguinal hernia repairs

    Hernia : the journal of hernias and abdominal wall surgery

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