Measured glomerular filtration rate

2 papers1 finding

Human trial1
Humans1

Interventions

1

Dapagliflozin

downin humans1

1 study

Dapagliflozin decreases measured glomerular filtration rate in humans (-6.6 mL/min per 1.73 m2 (-9.0 to -4.2; p<0.0001)).
“Compared with placebo, mGFR was changed with dapagliflozin treatment by -6·6 mL/min per 1·73 m2 (-9·0 to -4·2; p<0·0001) at week 6.”
Human trialnon-diabetic chronic kidney disease10 mg per day6 weeks
Effects of the SGLT2 inhibitor dapagliflozin on proteinuria in non-diabetic patients with chronic kidney disease (DIAMOND): a randomised, double-blind, crossover trial
The lancet. Diabetes & endocrinology1 Jul 2020

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