Macular pigment optical volume

1. Lutein + zeaxanthin is associated with macular pigment optical volume in humans (r = 0.22-0.30, P < 0.01).

   “weaker but significant for L&Z intake, and MPOV (r = 0.22-0.30, P < 0.01) of 3-mm-diameter macula lutea only, for eAMD and iAMD.”

   Humans3-mm-diameter macula lutea in eAMD and iAMDretinan = 369

   Xanthophyll Carotenoid Intake, Plasma Levels, and Retinal Visualization in Aging and Age-Related Macular Degeneration: ALSTAR2

   Investigative ophthalmology & visual science·1 Jul 2026

More on Lutein + zeaxanthin

1. Plasma lutein and zeaxanthin is associated with macular pigment optical volume in humans (r = 0.41-0.67, P < 0.01).

   “Associations were strong between plasma L&Z and MPOV (r = 0.41-0.67, P < 0.01)”

   Humansadjusted for age and HDL/LDLretinan = 369

   Xanthophyll Carotenoid Intake, Plasma Levels, and Retinal Visualization in Aging and Age-Related Macular Degeneration: ALSTAR2

   Investigative ophthalmology & visual science·1 Jul 2026

More on Plasma lutein and zeaxanthin