Lp(a) particle concentration

1. Lp(a) particle concentration increases guideline-based risk category in humans (2.9% reclassified higher versus 1.5% lower; 95.6% category agreement).

   “Molar assigned 2.9% of individuals to a higher risk category than mass, vs 1.5% in the opposite direction.”

   HumansMolar versus mass-based Lp(a) reportingn = 3,898

   Lipoprotein(a): Particle vs mass and prevalent cardiovascular disease in the cardiovascular risk in Young Finns study population

   Journal of clinical lipidology·25 Sep 2026

More on Guideline-based risk category

1. Lp(a) particle concentration is associated with coronary artery disease in humans (OR 1.55, highest versus lowest quintile).

   “In fully adjusted CAD models, the odds ratio for the highest vs lowest quintile was 1.55 for molar and 1.67 for mass.”

   HumansFully adjusted model; highest versus lowest quintilen = 3,898

   Lipoprotein(a): Particle vs mass and prevalent cardiovascular disease in the cardiovascular risk in Young Finns study population

   Journal of clinical lipidology·25 Sep 2026

More on Coronary artery disease