Low WMH volume

1. Low WMH volume decreases ventricular volume in humans.

   “The low group had lower mean ventricular volumes than the remaining and high groups.”

   Humanscompared to remaining and high groups

   Evidence and Characteristics of Favorable Aging Group Within the Framingham Heart Study

   AAIC 2025 abstract·23 Dec 2025

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1. Low WMH volume decreases gray matter volume loss in humans.

   “Separate regression modeling found significantly less age‐related gray matter volume loss compared to the high group”

   Humanscompared to high WMH group

   Evidence and Characteristics of Favorable Aging Group Within the Framingham Heart Study

   AAIC 2025 abstract·23 Dec 2025

1. Low WMH volume lowers the risk of hypertension in humans.

   “The low group also had significantly lower systolic blood pressure, rates of hypertension, and Framingham Stroke Risk Profile Scores compared to the remaining and high groups”

   Humanscompared to remaining and high groups

   Evidence and Characteristics of Favorable Aging Group Within the Framingham Heart Study

   AAIC 2025 abstract·23 Dec 2025

More on Hypertension