1 paper2 findings
Systolic blood pressure
upin silico1
Systolic blood pressure increases load-dependent arterial stiffness in silico (P<0.001).
“With Mendelian randomization, SBP and DBP showed significant independent positive effects on load-dependent stiffness (P<0.001)”
In silicon = 5,804
Blood pressure gene scores linked to artery stiffness
Journal of the American Heart Association10 Oct 2026
Systolic blood pressure polygenic risk score
upin humans1
Systolic blood pressure polygenic risk score is associated with load-dependent arterial stiffness in humans (β=0.09±0.01, P=7.93×10−30).
“Load-dependent carotid PWV was associated with the SBP PRS (β=0.09±0.01, P=7.93×10−30)”
Humansn = 5,804
Blood pressure gene scores linked to artery stiffness
Journal of the American Heart Association10 Oct 2026
An observational study of 5,804 people linked blood pressure gene scores to pressure-related artery stiffness, but not to structural stiffness associated with aging.An observational study of 5,804 people linked blood pressure gene scores to pressure-related artery stiffness, but not to structural stiffness associated with aging.