LEP promoter methylation

LEP promoter methylation is associated with metabolic health in humans.

“Pre-intervention: higher Leptin methylation was generally associated with better metabolic profiles in the MHO group.”

Humansmetabolically healthy Egyptian women with obesity, before dietary interventionfemalesn = 35

Metabolic risk factors and leptin DNA methylation dynamics in a sample of Egyptian women with obesity

Scientific reports·15 Oct 2026