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LECT2

Biomarker

2 papers3 findings

  • Humans1
  • Animals1

Associations

3

Handgrip strength

downin humans1

1 study

  1. LECT2 is associated with handgrip strength in humans (r = -0.474, p < 0.001).

    “Circulating LECT2 levels were inversely correlated with ASM/BMI (r = -0.506, p < 0.001) and HGS/BMI (r = -0.474, p < 0.001)”

    Humansn = 400

    Plasma Leukocyte Cell-Derived Chemotaxin-2 as a Risk Factor of Sarcopenia: Korean Frailty and Aging Cohort Study

    Nutrients14 Apr 2025

Non-alcoholic fatty liver disease

upin humans1

1 study

  1. Non-alcoholic fatty liver disease is associated with LECT2 in humans (34.4 vs 29.0 ng/mL, p < 0.001).

    “The participants with NAFLD had significantly higher plasma LECT2 levels compared to their non-NAFLD counterparts (34.4 [29.3-41.1] vs. 29.0 [24.7-36.7] ng/mL, p < 0.001).”

    Humansfatty liver index > 30n = 400

    Plasma Leukocyte Cell-Derived Chemotaxin-2 as a Risk Factor of Sarcopenia: Korean Frailty and Aging Cohort Study

    Nutrients14 Apr 2025

More on Non-alcoholic fatty liver disease

Sarcopenia

upin humans1OR 5.48

1 study

  1. LECT2 raises the risk of sarcopenia in humans (OR 5.48, 95% CI 1.57-19.05).

    “the highest LECT2 quartile had markedly greater odds of an LMM (OR 3.31, 95% CI 1.41-7.75), LMS (OR 2.85, 95% CI 1.29-6.26), and sarcopenia (OR 5.48, 95% CI 1.57-19.05) relative to the lowest quartile.”

    Humansn = 400

    Plasma Leukocyte Cell-Derived Chemotaxin-2 as a Risk Factor of Sarcopenia: Korean Frailty and Aging Cohort Study

    Nutrients14 Apr 2025

More on Sarcopenia

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