Lean body mass loss

There is 1 paper on lean body mass loss in aging research: none in people yet, 1 review.

Biomarker

1 paper studies it17 more mention it2 findings

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Interventions

2

Tirzepatide

upin humans1

1 study
  1. Tirzepatide increases lean body mass loss in humans (compared with semaglutide in routine care).

    “tirzepatide exhibits greater absolute LBM reduction than semaglutide in routine care”

    Reviewcompared with semaglutide in routine care

    Comparative incidence of sarcopenia across distinct GLP-1 receptor agonists in non-diabetic populations

    International Health Sciences Review

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Incretin therapy

upin humans1+25% weight lost is lean mass

1 study
  1. Incretin therapy induces lean body mass loss in humans during weight loss (approximately 25% of weight lost is lean mass).

    “Clinical trials and real-world EHR phenotyping confirm that these therapies induce weight loss characterized by a consistent partitioning ratio—approximately 75% fat and 25% lean mass loss.”

    Reviewduring weight loss

    Comparative incidence of sarcopenia across distinct GLP-1 receptor agonists in non-diabetic populations

    International Health Sciences Review

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Latest

Nov 2025: 1Dec 2025: 0Jan 2026: 1Feb 2026: 1Mar 2026: 0Apr 2026: 0May 2026: 2Jun 2026: 0Jul 2026: 1Aug 2026: 2Sep 2026: 1Oct 2026: 09 papers in 12 months

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