Insoluble poly-ubiquitinated proteins
3 papers2 findings
- Model organisms3
Upstream
1eff
downin flies2
2 studies
eff
downin flies2
eff decreases insoluble poly-ubiquitinated proteins in flies.
“muscle-specific eff knockdown causes an accelerated buildup in insoluble poly-ubiquitinated proteins”
Model organismsmuscle-specific knockdownskeletal muscle
eLife26 Feb 2024Preprint
eff decreases insoluble poly-ubiquitinated proteins in flies.
“muscle-specific eff knockdown causes an accelerated buildup in insoluble poly-ubiquitinated proteins (which progressively accumulate with aging) and shortens lifespan.”
Model organismsmuscle-specific eff knockdownskeletal muscle
eLife26 Feb 2024Preprint
Latest
PLOS Biology
The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity
Experiments in model organismsMechanisms
eLife
The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
Preprint: experiments in fliesProteostasis
eLife
The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
Preprint: experiments in fliesProteostasis
eLife
The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
Preprint: experiments in fliesProteostasis