Infection-induced ABC

1. Whole inactivated influenza virus vaccine induces infection-induced ABC in mice.

   “Immunization with whole inactivated virus also generates iABC in aged mice.”

   Animals

   IgD⁺ age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

   Aging cell·Sep 2, 2022

More on Whole inactivated influenza virus vaccine

1. TLR9 is required for infection-induced ABC in mice.

   “The response of ABC to influenza infection, resulting in iABC, is T cell independent and requires both extrinsic TLR7 and TLR9 signals.”

   Animalsresponse of ABC to influenza infection resulting in iABC

   IgD⁺ age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

   Aging cell·Sep 2, 2022

More on TLR9

1. TLR7 is required for infection-induced ABC in mice.

   “The response of ABC to influenza infection, resulting in iABC, is T cell independent and requires both extrinsic TLR7 and TLR9 signals.”

   Animalsresponse of ABC to influenza infection resulting in iABC

   IgD⁺ age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

   Aging cell·Sep 2, 2022

More on TLR7