Immune clock

1 paper1 finding

Humans1

Associations

1

Cancer-related mortality

upin humans1HR 3.31

1 study

Immune clock predicts cancer-related mortality in humans (HR 3.31, 95% CI 1.78–6.17).
“only the Immune clock showed a significant positive association after multiple testing correction”
HumansParticipants without prior cancer diagnosis at baseline; lifestyle-adjusted model; 9 cancer-related deathsMean follow-up 10.6 years
Protein-based aging clocks linked to death risk in Finnish twins
medRxiv15 Oct 2026Preprint

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medRxiv2 h

Protein-based aging clocks linked to death risk in Finnish twins

Fifteen protein-based aging clocks were linked to death from any cause; 11 remained associated after lifestyle adjustment in 401 Finnish twins.Fifteen protein-based aging clocks were linked to death from any cause; 11 remained associated after lifestyle adjustment in 401 Finnish twins.

Preprint: cohort study of 401 peopleBiomarkers

bioRxiv20 Aug

Beyond point estimates: quantifying predictive uncertainty reveals hidden dimensions of biological age acceleration and improves risk interpretation

Preprint: cohort study in peopleBiomarkers

Frontiers in Immunology2 Jul

Accelerated immunosenescence in SLE: current evidence and clinical translation

ReviewMechanisms

Nature Communications11 Dec

Reading the immune clock: a machine learning model predicts mouse immune age from cellular patterns

Experiments in miceBiomarkers

Blood19 Aug

A T-cell-based metric of immune age predicts outcomes in older patients with myeloma receiving daratumumab-based therapy

Study in peopleBiomarkers

bioRxiv14 Mar

EpImAge: An Epigenetic-Immune Clock for Disease-Associated Biological Aging

Preprint: computational studyBiomarkers

Biomolecules27 Nov

Consumption of a Probiotic Blend with Vitamin D Improves Immunity, Redox, and Inflammatory State, Decreasing the Rate of Aging-A Pilot Study

Trial in peopleInterventions

Antioxidants27 Nov

Human Supplementation with AM3, Spermidine, and Hesperidin Enhances Immune Function, Decreases Biological Age, and Improves Oxidative-Inflammatory State: A Randomized Controlled Trial

Trial in peopleInterventions