IL-6, TNF-α, and C-reactive protein

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Mobility loss

upin humans1

1 study
  1. IL-6, TNF-α, and C-reactive protein is associated with mobility loss in humans.

    “Impaired appetite and increased inflammatory biomarkers are independently linked to mobility loss.”

    Humansindependent associationup to 6 yearsn = 3,073

    Poor appetite and inflammation linked to mobility loss

    Journal of the American Geriatrics Society12 Oct 2026

Appetite loss

upin humans1

1 study
  1. Appetite loss is associated with IL-6, TNF-α, and C-reactive protein in humans.

    “and had higher IL-6, TNF-α, and CRP levels (p < 0.001 for each).”

    Humansimpaired versus good appetitebaselinen = 3,073

    Poor appetite and inflammation linked to mobility loss

    Journal of the American Geriatrics Society12 Oct 2026

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Journal of the American Geriatrics Society

Poor appetite and inflammation linked to mobility loss

Over up to six years, 64% of participants aged 70–79 with poor appetite developed lasting mobility difficulties, compared with 47% with good appetite.Over up to six years, 64% of participants aged 70–79 with poor appetite developed lasting mobility difficulties, compared with 47% with good appetite.

Cohort study of 3,073 peoplePopulations