International Journal of Pharmaceutics
Single vaccine dose produced lasting immune responses in mice
Antibody responses persisted for 165 days after one dose, while immune cells from the spleen showed responses at 180 days.Antibody responses persisted for 165 days after one dose, while immune cells from the spleen showed responses at 180 days.
Mouse study · 5 miceBlood and immune system
Who was studied5 C57BL/6 mice, 165 days, against mice receiving soluble ovalbumin plus CpG
What changedAntibody responses lasted 165 days after one emulsion dose, while responses to soluble antigen plus CpG waned by 92 days
The catchCellular responses were measured after a booster, confounding the single-dose claim