IGFBP-7

1. Non-alcoholic steatohepatitis increases IGFBP-7 in mice.

   “IGFBP-7 was significantly increased in the serum in NASH compared with the controls.”

   Animalsin NASH compared with the controlsserum

   Insulin-like Growth Factor Binding Proteins and Cellular Senescence Are Involved in the Progression of Non-Alcoholic Fatty Liver Disease and Fibrosis in a Mouse Model

   Medicina (Kaunas, Lithuania)·2 Mar 2024

More on Non-alcoholic steatohepatitis

1. IGFBP-7 is associated with bladder cancer in humans.

   “remained associated with risk of bladder cancer, liver cancer, multiple myeloma, all-cause mortality, liver-related mortality, and diabetes.”

   Humansafter adjustment for aging-related proteins

   Circulating levels of insulin-like growth factor binding protein 7 are associated with risks of chronic diseases and death

   npj aging·9 May 2026

More on Bladder cancer

1. IGFBP-7 raises the risk of diabetes in humans.

   “Higher IGFBP-7 level was significantly associated with increased risk for liver cancer, all-cause mortality, diabetes, and other diseases.”

   Humans

   Circulating levels of insulin-like growth factor binding protein 7 are associated with risks of chronic diseases and death

   npj aging·9 May 2026

More on Diabetes

1. IGFBP-7 raises the risk of liver cancer in humans.

   “Higher IGFBP-7 level was significantly associated with increased risk for liver cancer, all-cause mortality, diabetes, and other diseases.”

   Humans

   Circulating levels of insulin-like growth factor binding protein 7 are associated with risks of chronic diseases and death

   npj aging·9 May 2026

More on Liver cancer

1. IGFBP-7 raises the risk of mortality in humans.

   “Higher IGFBP-7 level was significantly associated with increased risk for liver cancer, all-cause mortality, diabetes, and other diseases.”

   Humans

   Circulating levels of insulin-like growth factor binding protein 7 are associated with risks of chronic diseases and death

   npj aging·9 May 2026