IgD+ CD27+ marginal zone-like B cells

Chronological age is associated with IgD+ CD27+ marginal zone-like B cells in humans (r = −0.257).

“IgD + CD27 + marginal zone-like B cells declined significantly in Panel 1 ( r = −0.257, p = 0.009).”

Humanshealthy Chinese adultsperipheral bloodn = 103

Age-associated remodeling of NK cell subsets, B cell subsets, and T cell surface markers in peripheral blood of healthy Chinese adults: a prospective multicolor flow cytometry study

Frontiers in aging·9 Oct 2026