Hsa_circ_0036763

1. Hsa_circ_0036763 decreases cellular senescence in human cells.

   “Exogenous overexpression of hsa_circ_0036763 alleviated the senescence, collagen loss, and oxidative stress in IL-1β-induced NPCs”

   Cellsin IL-1β-induced nucleus pulposus cellsnucleus pulposus cells

   Hsa_Circ_0036763 is a Prognostic Biomarker for Intervertebral Disc Degeneration and Affects the Senescence and Collagen Loss of Nucleus Pulposus Cells via miR-4741/RGSL1

   Journal of investigative surgery : the official journal of the Academy of Surgical Research·29 Apr 2026

More on Cellular senescence

1. Hsa_circ_0036763 predicts intervertebral disk degeneration recurrence in humans (HR = 0.252, p = 0.002).

   “Its low expression predicted a higher risk of IDD recurrence (HR = 0.252, p = 0.002).”

   Humansin IDD patientsserumn = 120

   Hsa_Circ_0036763 is a Prognostic Biomarker for Intervertebral Disc Degeneration and Affects the Senescence and Collagen Loss of Nucleus Pulposus Cells via miR-4741/RGSL1

   Journal of investigative surgery : the official journal of the Academy of Surgical Research·29 Apr 2026

More on Intervertebral disk degeneration recurrence

1. Hsa_circ_0036763 is associated with modified Pfirrmann grade in humans (r = -0.675).

   “Serum hsa_circ_0036763 expression was negatively correlated with the modified Pfirrmann grade of IDD patients (r = -0.675).”

   Humansin IDD patientsserumn = 120

   Hsa_Circ_0036763 is a Prognostic Biomarker for Intervertebral Disc Degeneration and Affects the Senescence and Collagen Loss of Nucleus Pulposus Cells via miR-4741/RGSL1

   Journal of investigative surgery : the official journal of the Academy of Surgical Research·29 Apr 2026