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Hippocampal blood-brain barrier permeability

There is 1 paper on hippocampal blood-brain barrier permeability in aging research: 1 observational study in people.

Biomarker

1 paper studies it2 findings

See all 1 papers on hippocampal blood-brain barrier permeability

“hippocampal BBB permeability (beta = 0.142, SE = 0.050, p = 0.008) after correcting for age, education, and APOE4 status.”
Hippocampal blood-brain barrier permeability is related to the APOE4 mutation status of elderly individuals without dementiaJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020doi:10.1177/0271678x20952012
  • Humans1

Upstream

1

APOE

upin humans1

1 study

  1. APOE is linked with higher hippocampal blood-brain barrier permeability in humans (p = 0.007).

    “Hippocampal Ktrans was significantly higher in APOE4 carriers than in non-carriers (p = 0.007).”

    Humanshippocampus

    Hippocampal blood-brain barrier permeability is related to the APOE4 mutation status of elderly individuals without dementia

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

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Associations

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Cognitive functioning

upin humans1

1 study

  1. Hippocampal blood-brain barrier permeability predicts cognitive functioning in humans after adjustment for age, education, and APOE4 status (beta = 0.142, SE = 0.050).

    “hippocampal BBB permeability (beta = 0.142, SE = 0.050, p = 0.008) after correcting for age, education, and APOE4 status.”

    Humansafter adjustment for age, education, and APOE4 statushippocampus

    Hippocampal blood-brain barrier permeability is related to the APOE4 mutation status of elderly individuals without dementia

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

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