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Ktrans

Biomarker

3 papers3 findings

  • Humans1
  • Animals1

Effects

1

Tau

no changein humans1

1 study

  1. Ktrans have no effect on Tau in humans.

    “There was not a significant relationship between Ktrans and FTP SUVR.”

    Humanscognitively normal older adultsbrainn = 31

    Associations between regional blood-brain barrier permeability, aging, and Alzheimer's disease biomarkers in cognitively normal older adults

    PloS oneJun 5, 2024

More on Tau

Upstream

1

APOE

upin humans1

1 study

  1. APOE increases Ktrans in humans.

    “OA who were APOE4 carriers had significantly higher Ktrans values.”

    Humanscognitively normal older adultsbrainn = 31

    Associations between regional blood-brain barrier permeability, aging, and Alzheimer's disease biomarkers in cognitively normal older adults

    PloS oneJun 5, 2024

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Associations

1

Amyloid-beta

upin humans1

1 study

  1. Ktrans are associated with amyloid-beta in humans.

    “SCCA showed increased Ktrans was associated with increased PiB DVR, mainly in temporal and parietal brain regions.”

    Humanscognitively normal older adultstemporal and parietal brain regionsn = 31

    Associations between regional blood-brain barrier permeability, aging, and Alzheimer's disease biomarkers in cognitively normal older adults

    PloS oneJun 5, 2024

More on Amyloid-beta

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