What does the research say about hemoglobin A1c-systolic blood pressure index?

Hemoglobin A1c-systolic blood pressure index

There are 2 papers on hemoglobin A1c-systolic blood pressure index in aging research: 2 observational studies in people. The newest story, Nov 9, 2026: “Health score linked to multiple diseases in older Chinese adults”.

Biomarker

2 papers study it2 findings

1 new paper in 30 daysSee all 2 papers on hemoglobin A1c-systolic blood pressure index

“Higher baseline HSI were significantly associated with increased risks of CVD”

Hemoglobin A1c-systolic blood pressure index as a novel predictor of cardiovascular disease: evidence from three prospective cohortsFrontiers in endocrinology2026doi:10.3389/fendo.2026.1718936

Humans2

Effects

Cardiovascular disease prediction performance

upin humans1

1 study

Hemoglobin A1c-systolic blood pressure index is linked with better cardiovascular disease prediction performance in humans (Compared with HbA1c or SBP alone).
“The predictive performance of HSI was superior to HbA1c or SBP alone.”
HumansCompared with HbA1c or SBP alone
Hemoglobin A1c-systolic blood pressure index as a novel predictor of cardiovascular disease: evidence from three prospective cohorts
Frontiers in endocrinologyFeb 18, 2026

Associations

Incident cardiovascular disease

upin humans1HR 1.16

1 study

Hemoglobin A1c-systolic blood pressure index is associated with incident cardiovascular disease in humans (Three population-based cohorts) (CHARLS: HR 1.16, 95% CI 1.11–1.22; ELSA: HR 1.13, 95% CI 1.06–1.21; HRS: HR 1.14, 95% CI 1.10–1.19).
“Higher baseline HSI were significantly associated with increased risks of CVD”
HumansThree population-based cohortsPer 1 SD increase in baseline HSI
Hemoglobin A1c-systolic blood pressure index as a novel predictor of cardiovascular disease: evidence from three prospective cohorts
Frontiers in endocrinologyFeb 18, 2026

Latest

2 papers in 12 months

Research SquareNov 6

Health score linked to multiple diseases in older Chinese adults

Higher starting scores were linked to 57% higher relative disease risk per standard deviation, a measure of variation, over approximately nine years.Higher starting scores were linked to 57% higher relative disease risk per standard deviation, a measure of variation, over approximately nine years.

Preprint: cohort · 6,279 peopleBiomarkers