Helios
1 paper1 finding
- Humans1
Upstream
1HELIOS
downin humans1
1 study
HELIOS
downin humans1
HELIOS decreases Helios in humans.
“Flow cytometry and western blotting revealed that the decline in Helios expression begins in the early neonatal period and persists across subsequent life stages.”
Humansfrom early neonatal period across life stagesnaive CD4-positive T cell
Helios expression in naive CD4+ T cells decreases from neonates to older adults
Clinical and experimental immunologyJan 6, 2026
Latest
4 in 12 monthsTransplantation and Cellular Therapy
Integrated Analysis of Hematopoietic Changes Following Heterochronic Bone Marrow Transplantation Between Young and Aged Mice
Experiments in miceBlood and immune system
Clinical and Experimental Immunology
Helios expression in naive CD4+ T cells decreases from neonates to older adults
Cohort study in peopleEpigenetic regulation of gene expression
Aging Cell
Perp Deficiency Induces Defective Negative Selection and Autoimmune Arthritis in Aged Mice
Experiments in miceMechanisms
ENDO 2025 Abstract
SAT-282 Renin-Independent Hyperaldosteronism Associated With Increased Risk of Hypertension and Metabolic Syndrome in a Multi-Ethnic Asian Cohort
Cross-sectional study of 1,395 peopleMetabolic syndrome
ADA Scientific Sessions 2025 Abstract
Helios+CD8 T Memory Cells, Enriched in Islet-Specific Cells of T1D Fast Progressors, Express Low Levels of CD2 and Inflammatory Cytokines
Cohort study in peopleInflammation
GSA 2024 Abstract
DISTINCT CELL SUBTYPES WITHIN NAÏVE CD4 T CELLS COMPARTMENT SHAPE ITS AGING AND SENESCENCE
Experiments in human cellsCellular senescence
Frontiers in Immunology
Co-Expression of TIGIT and Helios Marks Immunosenescent CD8⁺ T Cells During Aging
Study in peopleMechanisms